After her regeneration, the Doctor and the new Romana had about two years of adventures until she was written out of the cast in the 'Warriors Gate" story which was immediately followed by the stories leading to the Doctor''s regeneration.
Romana2 is played by Lalla Ward. (born 28 June 1951), She appears to be a generic intellectual, in addition to acting she's an artist and an author. She's currently married to biologist Richard Dawkins, a role she probably had to evolve into!